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Class of 2023
Session Information

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Session Title:
Control of Systemic Blood Flow
Teaching Hours:
Teaching and Learning MethodsTotal Scheduled Hours = 1
Lecture = 1
Control of Systemic Blood Flow
Translational Medical Research

Teaching and Learning Methods
Lecture 1 hour(s)

Learning Objectives
Blueprint ID Learning Objectives
7822 Describe the importance of blood pressure in maintaining blood flow to organs
7823 Describe the influence of organ vascular resistance to flow in governing the partitioning of cardiac output to organs and in governing total systemic resistance to blood flow
7824 Describe the relative hierarchy of blood flow to organs at rest, during exercise and under conditions of stress such as vascular hemorrhage.
7825 Describe the general intrinsic and extrinsic mechanisms governing blood flow regulation within organs.
7826 Describe the vascular anatomy of the heart
7827 Compare whole brain vs. microscopic segmental cerebral blood flow (CBF) control in the brain.
7835 Describe the systolic/diastolic characteristics and level of coronary blood flow (CrBF) during each of these phases
7836 Describe the mechanisms regulating CrBF at rest and during exercise and the relative importance of metabolic control and autonomic nervous system control under the above conditions.
7837 Describe the influence of coronary artery stenosis, on coronary flow, coronary flow reserve and angina at rest and during exercise
7838 Describe CBF autoregulation in terms of the blood pressure ranges over which CBF is maintained constant, is decreased or increased with forced dilation.
7839 Describe the mechanisms promoting CBF autoregulation, pressure dependent vascular constriction and the mechanisms promoting metabolic control of CBF.
7840 Describe the role of nitric oxide in modulating CBF autoregulation and how this changes with disease
7841 Describe the effects of the sympathetic nervous system on CBF autoregulation
7842 Describe how the following diseases alter cerebral blood flow regulation and the physiological and pathological effects of these changes i. Hypertension ii. Hypertensive encephalopathy and effects of edema formation iii. Hemorrhagic stroke
7843 Describe the effects of low PaO2 and high PaCO2 on CBF autoregulation

Linked Course Goal(s) to Session
Blueprint ID Course Goals
7416 Integrate basic and clinical sciences as they relate to common clinical encounters and patient symptoms
Linked Program Competencies
To This Course Goal:
Linked Program Competencies To Course Goal(s)
me-6 Medical Expert
Apply knowledge of the clinical, socio-behavioural, and fundamental biomedical sciences relevant to a clinical problem.

Linked MCC Medical Expert Objectives