Blueprint ID | Learning Objectives |
6320 | Describe the role of the Krebs cycle (citric acid cycle) in intermediary metabolism. |
6321 | List the main sources of acetyl CoA used in the cycle. Define the origin of the major products of the cycle. Summarize the overall stoichiometry of the cycle. |
6322 | Determine the fate of the major products of the cycle. |
6323 | Describe the main parameters which regulate the activity of the cycle. |
6324 | Define the role of the electron transport chain and its relationship to oxidative phosphorylation. |
6325 | Explain how the oxidation of NADH is coupled to the phosphorylation of ADP by means of a trans-membrane proton gradient. |
6326 | Describe the parameters which regulate the rate of NADH oxidation. |
6327 | Describe the regulatory interrelationships between the Krebs Cycle and oxidative phosphorylation.
Explain how uncoupling agents affect ATP production and the rate of NADH oxidation. |
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