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Michiru Hirasawa

BioMedical Sciences
PhD, DVM

Professor of Neurosciences

e-mail: michiru@mun.ca

Centre for Interdisciplinary Obesity Research

Michiru Hirasawa Laboratory Facebook Page

Health Sciences Center

t: 709-864-6573 - Room 4337 (office)
f: 709-864-6007
lab: 709-864-6572 - Room 4334 (lab)



Research Interests

Obesity Facts 

Worldwide: > 1.9 billion overweight adults (>600 million obese) in 2014 (WHO)
Canada: 62% men and 46% women were overweight or obese in 2014   (Statistics Canada)
Obesity is a major risk factor for: type 2 diabetes, hypertension, stroke, cancer, depression, etc.
         
Combat Obesity: Our goal
To determine the cellular/molecular mechanisms underlying central control of energy balance (food intake and energy expenditure), which will identify new therapeutic targets for obesity and eating disorders.
 
Combat Obesity: Our approach
Interrogation of fundamental mechanisms underlying body weight regulation by the brain
  • Synaptic physiology
  • Ion channel functions
  • Transporters
  • Astrocyte-neuron communication
Investigation of the brain in obese/obesogenic conditions (diet-induced obesity; binge eating; yo-yo dieting; genetic obesity e.g. Prader-Willi Syndrome)
  • How does the brain change in obesogenic conditions?
  • How do these changes contribute to obesity?