Hematopathology (Lymph Nodes) Slides

Slide 1

Hodgkin's lymphoma

Slide 7

Mix small and large cleaved cells

Slide 2

Hodgkin's lymphoma

Slide 8

Large cleaved cells

Slide 3

Hodgkin's lymphoma

Slide 9

Large non-cleaved cells

Slide 4

Lymphocytic cells

Slide 10

Immunoblastic

Slide 5 

Follicular lymphoma

Slide 11

Lymphoblasts

Slide 6 

Small cleaved cells

LN-1-3

Hodgkin's disease:  All three show the mixed background which onsists of benign inflammatory cells - eosinophils, lymphocytes and plasma cells.

LN-1

Classic R-S cells with bilobed nucleus and mirror image nucleoli are seen.

LN-2

A mononuclear variant of a Hodgkin's cells is present in the lower right hand corner. It is a large cell with a large nucleus nucleolus.

LN-3

A variety of Hodgkin's cells are seen, including  a cell to the left, with a "popcorn-like" multilobated nucleus and prominent nucleolus.

LN- 4-11

Non-Hodgkin's lymphoma:  This series of slides points out the variety of cell sizes, shapes and other features which may be seen in the constellation of non-Hodgkin's lymphoma.  Note the absence of features of Hodgkin's disease, i.e. R-S cells and benign background cell and the overall "monotony" of the cell population.

LN-4

Well differentiated lymphocytic lymphoma:  small round lymphocytes with mature nuclear features, may be somewhat "plasmacytoid".

LN-5

The nodular or follicular pattern of architecture is seen in low grade and a few of the intermediate grade lymphomas.

LN-6

Small cleaved cells (low grade lymphoma).

LN-7

Mixed small and large cells (low or intermediate grade, depending on the architectural pattern which cannot be determined from this slide.

LN-8

Large cleaved cells (Intermediate grade lymphoma).

LN-9

Large non-cleaved cell lymphomas - aside from being larger in size these nuclei are more immature and may show several small but prominent nucleoli (Intermediate grade lymphomas)

LN-10

Immunoblastic cells - large with more prominent nucleoli (High grade lymphoma)