Liver Pathology Slides
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L-1 |
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Diagrammatic representation of scanning EM view of liver tissue. (From the Liver - An Atlas of Scanning Electron Microscopy, by P. Motta, M. Mutto and T. Fujita). |
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CV - Central vein, K-Kupffer cell, FSC - Fat storing cell, | |
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BC - Bile canaliculus, EN - Endothelial cell, S - Sinusoid populated with large and small fenestrations, | ||
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DS - Disse's space, | ||
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HAb - Hepatic Artery branch, PVb - Portal Vein branch, | ||
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CDJ - Canaliculo-ductular junction | ||
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BDI - Bile ductule | ||
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LmP - Limiting plate | ||
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L - Liver plates | ||
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L-2 |
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L-3 |
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Sequence of serologic changes in acute hepatitis A |
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L-4 |
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A diagrammatic representation of Hepatitis B virus. (Abbott Diagnostics Laboratory). |
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L-5 |
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Sequences of serologic changes in acute hepatitis B. |
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L-6 |
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Acute lobular hepatitis showing diffuse portal lymphocytes and mononuclear cell infiltration, disruption of marginal plate, Kupffer cell hyperplasia, and disarray of cell cord. |
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L-7 |
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Acute viral hepatitis, lobular inflammation, focal necrosis with loss of liver cells, ballooning changes, acidophilic bodies, disarray of cell rods, hypertrophy and hyperplasia of liver cells, cholestasis and pigmentary macrophages. |
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L-8 |
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Submassive bridging necrosis in an elderly person. The collapsed passive septae show bridging of the lobular landmarks (portal-portal, portal-central and central-central). |
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L-9 |
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Gross appearance of liver from a fatal case of acute hepatitis. Multiple confluent areas of necrosis, which are congestive in nature, are about 50% of the entire liver mass. |
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L-10 |
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Fulminant hepatitis with massive liver necrosis (the so-called acute liver atrophy). The liver weighed 800 gms showing green-yellow residual liver mass and dark red necrotic areas. The capsule is wrinkled. |
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L-11 |
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Massive hepatic necrosis, leaving only portal structures intact. |
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L-12 |
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Chronic persistent hepatitis showing intact liver limiting plate, enlarged portal tract with chronic inflammatory infiltration. |
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L-13 |
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Ground-glass cells of HBsAg in chronic carrier state. |
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L-14 |
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Chronic active hepatitis in its early stage. Note the erosion of marginal plate (so-called piecemeal necrosis). |
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L-15 |
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Higher magnification of a focus showing piecemeal necrosis of marginal plate due to mononuclear, lymphocytic and plasma cell infiltration. Notice the hepatic cells trapped in the inflammatory front have undergone lysis. |
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L-16 |
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Advanced state of chronic active hepatitis, showing heavy and active inflammatory infiltration, bridging of septae, disarray of cell cords and many pseudoacinar formation of liver cells in attempt of regeneration. |
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L-17 |
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Severe disruption of cell cords and chronic inflammation in a florid example of CAH. |
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L-18 |
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Marked fatty liver in acute alcoholism. |
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L-19 |
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Alcoholic hepatitis, showing disarray of cell cord, swelling of liver cells, which contain Mallory hyalin. There are small amounts of fatty change, fibrosis in lobule and leucocytic infiltrations. Cholestasis is prominent. |
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L-20 |
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Alcoholic hepatitis showing florid acute inflammatory infiltration, cellular swelling, necrosis, presence of Mallory hyalin, some fatty change and sclerosis of pericellular frameworks. |
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L-21 |
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A classical example of alcoholic cirrhosis. Finely granular surface and cut surface, fine scars and tawny yellow colour due to fatty change. |
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L-22 |
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Microscopic appearance of micronodular cirrhosis (trichrome stain). |
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L-23 |
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The cross section of the liver showing fibrous scar, mostly in left lobe involving outer portion of hepatic parenchyma. The liver is icteric. |
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L-24 |
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Macronodular cirrhosis showing irregular size of nodule. |
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L-25 |
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Pigmentary cirrhosis of hemochromatosis. Notice the typical dark chocolate colour and micronodularity of the liver tissue. |
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L-26 |
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An iron stain of hemochromatosis showing marked parenchymatous iron deposition. |
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L-27 |
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Primary biliary cirrhosis, showing dark green cholestatic liver, and an apparent nodularity though vaguely definable. |
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L-28 |
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Hemangioma of liver. |
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L-29 |
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Microscopy of liver hemangioma. |
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L-30 |
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Cystic lesions of liver. |
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L-31 |
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A liver cell carcinoma arising from cirrhotic liver. Notice the expansile growth, jaundiced parenchyma. |
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L-32 |
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Liver cell carcinoma with hepatic vein invasion. |
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L-33 |
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Liver cell carcinoma. |
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L-34 |
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Microscopy of the portal tract in a patient with Primary Biliary Cirrhosis. The bile duct shows non-suppurative destructive cholangitis. There is a small granuloma beside the inflamed bile duct. |
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L-35 |
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Large granulomas in portal tracts and lobules in a patient with sarcoidosis. |
