FACULTY OF MEDICINE "Building a Healthy Tomorrow" TM
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Bibliography 2004 -
Dan LA, Werdyani S, Xu J, Shestopaloff K, Hyde A, Dicks E, Younghusband B, Green J, Parfrey P, Xu W, Savas S. No associations of a set of SNPs in the Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinase (MMP) genes with survival of colorectal cancer patients. Cancer Medicine. 2016 Sep; 5(9):2221-31. doi: 10.1002/cam4.796
Haja Mohideen AM, Hyde A, Squires J, Wang J, Dicks E, Younghusband B, Parfrey P, Green R, Savas S. Examining the polymorphisms in the hypoxia pathway genes in relation to outcome in colorectal cancer. PLoS One. 2014 Nov 18; 9(11):e113513. doi: 10.1371/journal.pone.0113513
Negandhi AA, Hyde A, Dicks E, Pollett W, Younghusband BH, Parfrey P, Green RC, Savas S. MTHFR Glu429Ala and ERCC5 His46His Polymorphisms Are Associated with Prognosis in Colorectal Cancer Patients: Analysis of Two Independent Cohorts from Newfoundland. PLoS One. 2013 Apr 23; 8(4):e61469. doi: 10.1371/journal.pone.0061469
Clarke E, Green RC, Green JS, Mahoney K, Parfrey PS, Younghusband HB, Woods MO . Inherited deleterious variants in GALNT12 are associated with CRC susceptibility. Human Mutation. 2012 Jul; 33(7):1056-8. doi: 10.1002/humu.22088
Savas S, Hyde A, Stuckless SN, Parfrey P, Younghusband HB, Green R. Serotonin Transporter Gene (SLC6A4) Variations Are Associated with Poor Survival in Colorectal Cancer Patients. PLoS One. 2012; 7(7):e38953. doi: 10.1371/journal.pone.0038953
Rawson JB, Manno M, Mrkonjic M, Daftary D, Dicks E, Buchanan DD, Younghusband HB, Parfrey PS, Young JP, Pollett A, Green RC, Gallinger S, McLaughlin JR, Knight JA, Bapat B. Promoter methylation of Wnt antagonists DKK1 and SFRP1 is associated with opposing tumor subtypes in two large populations of colorectal cancer patients Carcinogenesis. 2011 May; 32(5):741-7. doi: 10.1093/carcin/bgr020
Rawson JB, Mrkonjic M, Daftary D, Dicks E, Buchanan DD, Younghusband HB, Parfrey PS, Young JP, Pollett A, Green RC, Gallinger S, McLaughlin JR, Knight JA, Bapat B. Promoter methylation of Wnt5a is associated with microsatellite instability and BRAF V600E mutation in two large populations of colorectal cancer patients. British Journal of Cancer. 2011 Jun 7; 104(12):1906-12. doi: 10.1038/bjc.2011.165
Hyde A, Fontaine D, Stuckless S, Green R, Pollett A, Simms M, Sipahimalani P, Parfrey P, Younghusband B. A histology-based model for predicting microsatellite instability in colorectal cancers. The American Journal of Surgical Pathology. 2010 Dec; 34(12):1820-9. doi: 10.1097/PAS.0b013e3181f6a912
Campbell PT, Jacobs ET, Ulrich CM, Figueiredo JC, Poynter JN, McLaughlin JR, Haile RW, Jacobs EJ, Newcomb PA, Potter JD, Le Marchand L, Green RC, Parfrey P, Younghusband HB, Cotterchio M, Gallinger S, Jenkins MA, Hopper JL, Baron JA, Thibodeau SN, Lindor NM, Limburg PJ, Martínez ME; Colon Cancer Family Registry. Case-control study of overweight, obesity, and colorectal cancer risk, overall and by tumor microsatellite instability status. Journal of the National Cancer Institute. 2010 Mar 17; 102(6):391-400. doi: 10.1093/jnci/djq011
10  Savas S, Younghusband HB. dbCPCO: a database of genetic markers tested for their predictive and prognostic value in colorectal cancer. Human Mutation. 2010 Aug; 31(8):901-7. doi: 10.1002/humu.21285
11  Wish TA, Hyde AJ, Parfrey PS, Green JS, Younghusband HB, Simms MI, Fontaine DG, Dicks EL, Stuckless SN, Gallinger S, McLaughlin JR, Woods MO, Green RC. Increased cancer predisposition in family members of colorectal cancer patients harboring the p.V600E BRAF mutation: a population-based study. Cancer Epidemiology, Biomarkers and Prevention. 2010 Jul; 19(7):1831-9. doi: 10.1158/1055-9965.EPI-10-0055
12  Squires J, Roebothan B, Buehler S, Sun Z, Cotterchio M, Younghusband B, Dicks E, McLaughlin JR, Parfrey PS, Wang PP. Pickled meat consumption and colorectal cancer (CRC): a case-control study in Newfoundland and Labrador, Canada. Cancer Causes & Control. 2010 Sep; 21(9):1513-21. doi: 10.1007/s10552-010-9580-z
13  Mrkonjic M, Roslin NM, Greenwood CM, Raptis S, Pollett A, Laird PW, Pethe VV, Chiang T, Daftary D, Dicks E, Thibodeau SN, Gallinger S, Parfrey PS, Younghusband HB, Potter JD, Hudson TJ, McLaughlin JR, Green RC, Zanke BW, Newcomb PA, Paterson AD, Bapat B. Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer. PLoS One. 2010 Oct 13; 5(10):e13314. doi: 10.1371/journal.pone.0013314
14  Woods MO, Younghusband HB, Parfrey PS, Gallinger S, McLaughlin J, Dicks E, Stuckless S, Pollett A, Bapat B, Mrkonjic M, de la Chapelle A, Clendenning M, Thibodeau SN, Simms M, Dohey A, Williams P, Robb D, Searle C, Green JS, Green RC. The genetic basis of colorectal cancer in a population-based incident cohort with a high rate of familial disease. Gut. 2010 Oct; 59(10):1369-77. doi: 10.1136/gut.2010.208462
15  Cleary SP, Cotterchio M, Jenkins MA, Kim H, Bristow R, Green R, Haile R, Hopper JL, LeMarchand L, Lindor N, Parfrey P, Potter J, Younghusband B, Gallinger S. Germline MutY human homologue mutations and colorectal cancer: a multisite case-control study. Gastroenterology. 2009 Apr; 136(4):1251-60. doi: 10.1053/j.gastro.2008.12.050
16  Green RC, Parfrey PS, Woods MO, Younghusband HB. Prediction of Lynch syndrome in consecutive patients with colorectal cancer. Journal of the National Cancer Institute. 2009 Mar 4; 101(5):331-40. doi: 10.1093/jnci/djn499
17  Wang PP, Dicks E, Gong X, Buehler S, Zhao J, Squires J, Younghusband B, McLaughlin JR, Parfrey PS. Validity of random-digit-dialing in recruiting controls in a case-control study. American Journal of Health Behavior. 2009 Sep-Oct; 33(5):513-20. doi: 10.5993/AJHB.33.5.4
18  Woods MO, Williams P, Careen A, Edwards L, Bartlett S, McLaughlin JR, Younghusband HB. A new variant database for mismatch repair genes associated with Lynch syndrome. Human Mutation. 2007 Jul; 28(7):669-73. doi: 10.1002/humu.20502
19  Kuch M, Grocke DR, Knyf MC, Gilbert MT, Younghusband B, Young T, Marshall I, Willerslev E, Stoneking M, Poinar H. A preliminary analysis of the DNA and diet of the extinct Beothuk: a systematic approach to ancient human DNA. American Journal of Physical Anthropology. 2007 Apr; 132(4):594-604. doi: 10.1002/ajpa.20536
20  Campbell P, Edwards L, McLaughlin J, Green J, Younghusband HB, Woods MO. Cytochrome P450 17A1 and catechol O-methyltransferase polymorphisms and age at Lynch syndrome colon cancer onset in Newfoundland Clinical Cancer Research. 2007 Jul 1; 13(13):3783-8. doi: 10.1158/1078-0432.CCR-06-2987
21  Zanke BW, Greenwood CM, Rangrej J, Kustra R, Tenesa A, Farrington SM, Prendergast J, Olschwang S, Chiang T, Crowdy E, Ferretti V, Laflamme P, Sundararajan S, Roumy S, Olivier JF, Robidoux F, Sladek R, Montpetit A, Campbell P, Bezieau S, O'Shea AM, Zogopoulos G, Cotterchio M, Newcomb P, McLaughlin J, Younghusband B, Green R, Green J, Porteous ME, Campbell H, Blanche H, Sahbatou M, Tubacher E, Bonaiti-Pellié C, Buecher B, Riboli E, Kury S, Chanock SJ, Potter J, Thomas G, Gallinger S, Hudson TJ, Du. Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nature Genetics. 2007 Aug; 39(8):989-994. doi: 10.1038/ng2089
22  Goldberg YP, MacFarlane J, MacDonald ML, Thompson J, Dube MP, Mattice M, Fraser R, Young C, Hossain S, Pape T, Payne B, Radomski C, Donaldson G, Ives E, Cox J, Younghusband HB, Green R, Duff A, Boltshauser E, Grinspan GA, Dimon JH, Sibley BG, Andria G, Toscano E, Kerdraon J, Bowsher D, Pimstone SN, Samuels ME, Sherrington R, Hayden MR . Loss-of-function mutations in the Na(v)1.7 gene underlie congenital indifference to pain in multiple human populations. Clinical Genetics. 2007 Apr; 71(4):311-9. doi: 10.1111/j.1399-0004.2007.00790.x
23  Raptis S, Mrkonjic M, Green RC, Pethe VV, Monga N, Chan YM, Daftary D, Dicks E, Younghusband BH, Parfrey PS, Gallinger SS, McLaughlin JR, Knight JA, Bapat B. MLH1 -93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer. Journal of the National Cancer Institute. 2007 Mar 21; 99(6):463-74. doi: 10.1093/jnci/djk095
24  Mrkonjic M, Raptis S, Green RC, Monga N, Daftary D, Dicks E, Younghusband HB, Parfrey PS, Gallinger SS, McLaughlin JR, Knight JA, Bapat B. MSH2 118T>C and MSH6 159C>T promoter polymorphisms and the risk of colorectal cancer. Carcinogenesis. 2007 Dec; 28(12):2575-80. doi: 10.1093/carcin/bgm229
25  Raptis S, Mrkonjic M, Green RC, Daftary D, Pethe V, Dicks E, Younghusband BH, Parfrey PS, Gallinger SS, McLaughlin JR, Knight JA, Bapat B. Re: MLH1 -93G > A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer - Response. Journal of the National Cancer Institute. 2007 Oct 3; 99(19):1490-1491. doi: 10.1093/jnci/djm140
26  Kokuer M, Naguib RN, Jancovic P, Younghusband HB, Green RC. Cancer risk analysis in families with hereditary nonpolyposis colorectal cancer. IEEE Transaction on Information Technology in Biomedicine. 2006 Jul; 10(3):581-587. doi: 10.1109/TITB.2006.872054
27  Green RC, Green JS, Buehler SK, Robb JD, Daftary D, Gallinger S, McLaughlin JR, Parfrey PS, Younghusband HB. Very high incidence of familial colorectal cancer in Newfoundland: a comparison with Ontario and 13 other population-based studies. Familial Cancer. 2006 Mar; 6(1):53-62. doi: 10.1007/s10689-006-9104-x
28  Kokuer M, G Naguib R, Jancovic P, Younghusband H, Green R. A comparison of multi-layer neural network and logistic regression in hereditary non-polyposis colorectal cancer risk assessment. Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2005; 3:2417-20. doi: 10.1109/IEMBS.2005.1616956
29  Sun G, French CR, Martin GR, Younghusband B, Green RC, Xie YG, Mathews M, Barron JR, Fitzpatrick DG, Gulliver W, Zhang H. Comparison of multifrequency bioelectrical impedance analysis with dual-energy X-ray absorptiometry for assessment of percentage body fat in a large, healthy population. American Journal of Clinical Nutrition. 2005 Jan; 81(1):74-8.
30  Woods MO, Hyde AJ, Curtis FK, Stuckless S, Green JS, Pollett AF, Robb JD, Green RC, Croitoru ME, Careen A, Chaulk JA, Jegathesan J, McLaughlin JR, Gallinger SS, Younghusband HB, Bapat BV, Parfrey PS. High frequency of hereditary colorectal cancer in Newfoundland likely involves novel sceptibility genes. Clinical Cancer Research. 2005 Oct 1; 11(19 Pt 1):6853-61. doi: 10.1158/1078-0432.CCR-05-0726
31  Green RC, McLaughlin JR, Younghusband HB. SISE matters: the sum of information on seventy-yr-old equivalents measures pedigree information content when assessing the risk of HNPCC in a family. Familial Cancer. 2005 Jun; 4(2):169-75. doi: 10.1007/s10689-004-7251-5
32  Cui J, Randell E, Renouf J, Sun G, Han FY, Younghusband B, Xie YG. Gender dependent association of Thrombospondin-4 A387P polymorphism with myocardial infarction. Arteriosclerosis, Thrombosis, and Vascular Biology. 2004 Nov; 24(11):e183-4. doi: 10.1161/01.ATV.0000147304.67100.ee
33  Kokuer M, Naguib R, Janeovie P, Younghusband H, Green R. Hereditary non-polyposis colorectal cancer risk assessment based on AI analysis of pedigree data. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 2004; 5:3229-32. doi: 10.1109/IEMBS.2004.1403909
34  Lafreniere RG, MacDonald ML, Dube MP, MacFarlane J, O'Driscoll M, Brais B, Meilleur S, Brinkman RR, Dadivas O, Pape T, Platon C, Radomski C, Risler J, Thompson J, Guerra-Escobio AM, Davar G, Breakefield XO, Pimstone SN, Green R, Pryse-Phillips W, Goldberg. Identification of a novel gene (HSN2) causing hereditary sensory and autonomic neuropathy type II through the Study of Canadian Genetic solates. American Journal of Human Genetics. 2004 May; 74(5):1064-73. doi: 10.1086/420795
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