Lymphatic System

The lymphatic vascular system collects fluid from the tissues and returns it to the venous circulation. The lymphatic system is able to remove debris from the fluid and sense and respond to the presence of antigens. In almost all cases lymph passes through at least one lymph node before returning to the circulation. The lymphatic vascular system is formed of superficial and deep components. The superficial system drains the skin and superficial tissues to collections of lymph nodes in the axilla and the inguinal region. From these two nodular areas the lymph passes to join the deep system. The deep system of lymphatics accompanies the vessels. The inguinal nodes continue into the external then common iliac nodes. The common iliac nodes also receive lymph from the internal iliac lymph nodes. The lymphatics then proceed cranially around the aorta. Lymphatics draining the territories of the inferior and superior mesenteric arteries, and the coeliac trunk drain into the para-aortic system. Lymphatics from the posterior abdominal wall drain alongside the lumbar arteries to reach the para-aortic lymphatics. Below the diaphragm the deep system of lymphatics drains into the cysterna chyli, a lymph sac lying behind the right crus of the diaphragm.

The thoracic duct leaves the cysterna chyli lying on the right side of the aorta and passes cranially lying in the posterior then superior mediastinum. As the thoracic duct passes upwards it moves towards the left, lying on the azygos system of veins. The thoracic duct drains into the venous system at the formation of the left brachiocephalic vein by the internal jugular and subclavian veins. The lymphatic vessels from the left side of the head and neck also drain into the venous system at this point, together with the lymphatics from the left axilla and left upper limb. The lymphatics from the right axilla and upper limb join those from the right side of the head and neck to drain into the formation of the right brachiocephalic vein.

Lymphatics of the thorax

The lymphatics of the thorax are considered fully in the Respiratory System Section. Lymph drains from the visceral pleura covering the lungs towards bronchopulmonary nodes that are located in the hilum of the lung. The lymph then passes to more proximal lymph nodes at the bifurcation of the trachea, the tracheobronchial lymph nodes. The deep tissues of the lung are drained by lymphatics that accompany the bronchi. These lymphatics again drain into the bronchopulmonary lymph nodes. The tracheobronchial, parasternal and anteriormediastinal lymph nodes on each side then form the bronchomediastinal limph nodes which drain towards the entry point to the venous system at the formation of the brachiocephalic veins. These lymphatic channels are in communication with the lymphatics of the breast and with those of the abdomen.

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