The sciatic nerve is formed in the pelvis by fibres from the lumbosacral trunk (L4,5) and by fibres
from S1,2,3. This thick nerve immediately leaves the pelvis through the greater sciatic notch,
below the piriformis muscle (P on diagram). The nerve may divide
immediately, or may pass either above the
piriformis or through the piriformis. In the gluteal region the nerve lies deep to gluteus maximus,
between the greater trochanter (GT) and the ischial tuberosity(IT). The
nerve then passes down the back of
the thigh to the apex of the popliteal fossa. In the thigh the nerve divides into lateral common
peroneal and medial tibial divisions. In the upper part of its course the sciatic nerve supplies the
semimembranosus, semitendinosus, the ischial head of adductor magnus and long head of biceps
femoris from its tibial division. The common peroneal division supplies fibres to the short head of
biceps femoris.
The deep peroneal nerve supplies the muscles of the anterior compartment - the tibialis anterior, extensor hallucis longus, extensor digitorum longus, peroneus tertius and extensor digitorum brevis. The deep peroneal nerve supplies cutaneous branches to the cleft between the big toe and the second toe.
The superficial peroneal nerve supplies the muscles in the lateral compartment (peroneus longus
and brevis) and the skin over the anterior lower leg and dorsum of the foot.
The sciatic nerve is commonly injured during intramuscular injections into the buttocks. The
nerve may also be injured by posterior dislocations or fracture dislocations of the hip joint. Injury
to the nerve might result in loss of the hamstrings and calf muscles resulting in loss of knee
flexion, and loss of the muscles of the anterior and lateral compartments of the leg resulting in
foot drop. Cutaneous sensation would be lost over the calf and dorsum, sole and lateral side of
the foot.
The common peroneal nerve may be injured as it winds around the neck of the fibula, resulting in foot drop (anterior compartment muscles), and loss of sensation on the lower anterior leg and dorsum of the foot. The nerve is also at risk in anterior compartment syndrome.
The roots of the nerve may also be compressed by a prolapsed disc, giving pain over part of the distribution of the nerve - sciatica.
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