Cellular Growth of the Skeleton

Cartilage

Hyaline Cartilage

The structure of hyaline cartilage suits it to its function as a weight-bearing surface in joints. In all of the synovial joints in the body hyaline cartilage covers the ends of the articulating bones. The cells of hyaline cartilage are derived initially from the cellular perichondrium. Cell division in this covering produces chondroblasts which are able to secrete the components of the matrix. Chondroblasts retain the ability to divide as they are separated from the perichondrium by the matrix. While embedded in the matrix chondroblasts divide to form chondrocytes occupying lacunae within the matrix. Growth of cartilage therefore can occur by addition of cells around the circumference from the perichondrium, appositional growth, and by cell division within the matrix, interstitial growth.

Elastic Cartilage

Elastic cartilage is flexible. It is found in the epiglottis, pinna of the ear, auditory tube and eustachian tube. It is organized in a similar way to hyaline cartilage with a perichondrium and chondroblasts and chondrocytes embedded in a matrix. The major difference is in the matrix where branched elastin fibres are present in addition to collagen.

Fibrocartilage

In fibrocartilage the structure is intermediate between that of hyaline cartilage and dense connective tissue. It is found where bones are bound together such as at the pubic symphysis and as part of intervertebral discs. There is no recognisable perichondrium. The cells are squeezed into rows by thick bundles of collagen fibres in the matrix. The collagen is orientated in the direction of stress. The gel component of the matrix is reduced compared to hyaline cartilage.

 

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