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Yagang Xie

Medicine
MD, Dr. Med Sci., FCCMG

Adjunct Professor


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Recent Publications

Roscioli T, Kennedy D, Cui J, Fonseca B, Watson GF, Pereira J, Xie Y-G, Mowat D. (2005) Pallister-Hall syndrome: Unreported skeletal features of a GLI3 mutation. Am J Med Genet A. 8;136A(4):390-394

Sun G, French C, Martin G, Younghusband B, Green R, Gulliver W,Xie Y-G, Matthews M, BarronĊ  J, Fitzpatrick D, Zhang H. (2005)Comparison of multi-frequency bioelectrical impedance analysis with dual-energy X-ray absorptiometry for the assessment of percent body fat in a large healthy population. American Journal of Clinical Nutrition, 81:74-78.

Ciu J, Randell E, Renou J, Sun G., Ban Y, Han F-Y and Xie Y-G.(2004) Gender Dependent association of Thrombospondin-4 A387P polymorphism with Myocardial infarction. Arterioscler Thromb Vasc Biol. 24(11):e183-4.

Xie Y-G. Butt C, Randell E (2003) Gene-gene interactions in myocardial infarction. Blood. 102 (4) 1559-1560.

Butt C, Zheng H, Randell E, Robb D, Parfrey P and Xie Y-G. (2002)Combined Carrier Status of Prothrombin 20210A and factor XIII-A L34 Alleles as a Strong Risk Factor for Myocardial Infarction: Evidence of a Gene-gene Interaction. Blood. 101(8):3037-41.

Fung K, Xie Y-G, Hall SF, Lillicrap DP, Taylor SA. (2002) Genetic basis of familial Meniere's disease. J Otolaryngol 31(1):1-4

Zheng H, Tzeng C-C, Butt C, Randell E and Xie Y-G. (2002) Extremely Low Prevalence of Factor V Leiden, FII20210A and FXIIIV34L in Chinese Population. Thrombosis and Haemotasis. 87: 1081-2

Y-G. Xie, H. Zheng, J. Leggo,  P. M.-F. Scully, D. Lillicrap (2002): A founder factor VIII mutation, Valine 2016 to alanine, in a population with extraordinary high prevalence of mild hemophilia A.Thrombosis and Haemotasis. 87:178-9

Peyrard M, Seroussi E, Sandberg-Nordqvist AC, Xie Y-G, Han FY, Fransson I, Collins J, Dunham I, Kost-Alimova M, Imreh S, Dumanski JP. (1999) The human LARGE gene from 22q12.3-q13.1 is a new, distinct member of the glycosyltransferase gene family.Proc Natl Acad Sci U S A. 96 (2):598-603.

Xie Y-G, Lillicrap DP, Taylor SA (1998) An association between the common hereditary hemochromatosis mutation and the factor V Leiden allele in a population with thrombosis. Blood 15;92(4):1461-1462

Xie Y-G, Rochefort D, Brais B, Howard H, Han FY, Gou LP, Maciel P, The BT, Larsson C, Rouleau GA (1998) Restriction map of a YAC and cosmid contig encompassing the oculopharyngeal muscular dystrophy candidate region on chromosome 14q11.2-q13.Genomics 1;52(2):201-4

Brais B, Bouchard JP, Xie Y-G, Rochefort DL, Chretien N, Tome FM, Lafreniere RG, Rommens JM, Uyama E, Nohira O, Blumen S, Korczyn AD, Heutink P, Mathieu J, Duranceau A, Codere F, Fardeau M, Rouleau GA (1998) Short GCG expansions in the PABP2 gene cause oculopharyngeal muscular dystrophy. Nature Genetics, 18(2):164-7
Cui J, Randell E, Renouf  J, Sun G,  Han FH, and Xie  Y-G (2006) Study of the Association between Common Gene Variants of Coagulation Factor XIII and Myocardial Infarction.  6th Human Genome Organization (HUGO) Pacific Meeting &7th Asia-Pacific Human Genetics Conference (HUGO-AP 2006) (Taipei, March 2006)

Scully MF, MacGregor D , Walsh M , Barrett,Dr. B , Kawaja M3,  Harvey M, Hendry, M, Sheppard C, Stuckless S, Xie Y-G  (2005) The clinical impact of mild hemophilia A, report of a cohort study. The American Society of Hematology 47th Annual Meeting (Atlanta, Dec. 2005) Post presentation.

Xie Y-G (2005) Molecular Genetic testing as Clinical Service in a Genetic Isolated Population. Oral presentation, 2005 World DNA and Genome Day (Dalian, April25 -30), Abstract book pp230

Cui J., Randell E. Renouf  J , Sun G., Han F-Y, Green R. and Xie Y-G (2005) The Impact of Factor XIII Polymorphisms, FXIIIa T204P, P506L and Factor XIIIb Polymorphism H95A, on Myocardial Infarction. Subunit Deficiency in Newfoundland population. International Society of Thrombosis and Haemostasis XXth Congress (Sydney, August 2005)

Scully MF, ,MacGregor D , Walsh M   Barrett,Dr. B  , Kawaja M , Hann A,  Harvey M  ,Hendry M ,Mulcahey R, Sheppard C,Stuckless S, Taylor M, , Xie Y-G (2005) Preliminary Results of a Cross-Sectional Study of Mild Hemophilia  A in Newfoundland and Labrador, Canada. International Society of Thrombosis and Haemostasis XXth Congress (Sydney, August 2005)

 Zheng H, Cui J, Scully M-F, David Macgregor D, Hendry M, Harvey M, Xie Y-G (2005), Molecular Defect of Factor XIII A Subunit in Newfoundland Families with Factor XIII A Subunit Deficiency. International Society of Thrombosis and Haemostasis XXth Congress (Sydney, August 2005)

Xie Y-G, Zheng H, Cui J, Scully M-F, David Macgregor D, Hendry M, Harvey M (2005), Identification of a Splicing Mutation in Four Newfoundland Families with Factor XIII A Subunit Deficiency. Annual Meeting of American Society of Medical Genetics (Dallas, March 2005)
 

Abstracts

Ciu J, Randell E, Renou J, Sun G., Ban Y and Xie Y-G. (2004)Gender Dependent association of Thrombospondin-4 A387P polymorphism with Myocardial infarction. Annual Meeting of American Society of Human Genetics (Toronto, Oct. 2004)

J. Xu, T. Heshka, D. Whelan, J-X. Cui, F-Y. Han, Y-G. Xie (2004)Molecular cytogenetics characterization of trisomy 13/trisomy 18 mixoploidy in a boy with moderate clinical features. Annual Meeting of American Society Human Genetics (Toronto, Oct. 2004)

Martin G, French C, Randell E, Roebothan B, Green R, Younghusband B, Xie Y-G, Mathews M, Zhang H, Sun G (2004)Calcium intake is correlated with percent body fat and percent trunk fat, but not serum lipids in the Newfoundland population. Obesity Research (supplement).

Walsh M, Macgregor D, Hann A, Barrett B, Xie Y-G, Mulcahy R, Harvey M, Hendry M, Taylor M, Scully M-F. (2004) Studies to Define the Clinical Impact of Mild Hemophilia A in Newfoundland & Labrador. Submitted to Hemophilia 2004 World Congress(Bangkok, Oct. 2004)

Martin G, French C, Randell E, Roebothan B, Green R, Younghusband B, Xie Y-G, Matthews M, Zhang H, Guang Sun.(2004) Calcium intake is correlated with percent body fat and percent trunk fat, but not lipids in the Newfoundland population.NAASO meeting (November, 2004)

Xie Y-G, Butt C, Zheng H, Randell E, Robb D,  Parfrey P (2003)  Evidence of gene-gene interaction as a strong risk factor for myocardial infarction: Combined carrier status of prothrombin 20210A and factor XIII-A L34 alleles. American Journal Human Genetics 73: 375.

Butt C, Zheng H, Randell E, Robb D, Parfrey P and Xie Y-G. (2003)Combined carrier status of prothrombin 20210A and factor XIII-A L34 alleles: evidence as a strong risk factor for myocardial infarction. XIX Congress of the International Society on Thrombosis and Haemostasis (Birmingham, UK 2003). Published at Journal ofThrombosis and Haemostasis (Supplement ISSN 1740-3340) OC240

Scully MF, Barrett B, Hann H, Macgregor D, Walsh M, and Xie Y. (2003) Studies to define the clinincal impact of “mild” hemophilia A in a large kindre in Newfoundland and Laborador. Journal ofThrombosis and Haemostasis (Supplement ISSN 1740-3340) PO132

Butt C, Zheng H, Randell E, Robb D, Parfrey P and Xie Y-G. (2003)A strong risk factor for myocardial infarction: Combined carrier status of prothrombin 20210A and factor XIII-A L34 alleles. XIX International Congress of Genetics, (Melbourne, Australia 2003)

Macgregor D, Harvey M, Hendry M, Hann A, Sheppard C, Xie Y-G,Scully M-F (2002) Population characteristics and early lessons from a large Newfoundland kindred with so called ‘mild’ Factor VIII deficiency. Blood: 100 (11) 1923a

Zheng H, Tzeng C-C, Butt C, Randell E and Xie Y-G. (2002)Extremely Low Prevalence of Factor V Leiden, FII20210A and FXIIIV34L in Chinese Population. Eeuropean Journal of Human Genetics: 10 (Supplement 1) 189

Slaney D, Xie Y-G, Harvey M, Scully MF. (2001) Prophylactic treatment of FXIII deficiency with Fibrogammin. Blood 98(11): 261a.

R. Lush, P. Duggan, Y-G. Xie, M. Borgaonkar. (2001) Biochemical Abnormalities in Patients with one or more C282Y or H63D Mutations of the HFE Gene for Hereditary Hemochromatosis. TheAmerican Journal of Gastroenterology 96(Suppl):S129.

Zheng H, Butt C, Randell E, Porter M, Parfrey P and Xie Y-G. (2001) Factor XIII V34L, factor V Leiden, and prothrombin G20210A: relationship of common gene variants of blood coagulation factors to risk of myocardial infarction. European Journal of Human Genetics: 9 (Supplement 1) 369

Xie Y-G, Zheng H, Macgregor D, Leggo J, Bagnell R, Green P, Fernandez B, Robb D, Scully M-F, Lillicrap D. (2001) A founder factor VIII mutation, Valine 2016 to Alanine, in a population with extraordinary high prevalence of mild hemophilia A. Oral presentation at XVIII Congress of the International Society on Thrombosis and Haemostasis, published in Thrombosis and Haemostasis (Supplement ISSN 0340-6245) OC196

Zheng H, Butt C, Randell E, Porter M, Parfrey P and Xie Y-G. (2001) Prevalence of Factor XIII V34L, Factor V Leiden, and Prothrombin G20210A in Patients with Myocardial Infarction from a Relative Isolated Population. Oral presentation at XVIII Congress of the International Society on Thrombosis and Haemostasis, published in Thrombosis and Haemostasis (Supplement ISSN 0340-6245) OC95

Scully M-F, Hand J, Harvey M, Hendry M, Macgregor D, Xie Y-G. (2001) Report on the Hemophilia Program Registry for Newfoundland and Laborador. Thrombosis and Haemostasis(Supplement ISSN 0340-6245) CD3419
 
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