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Bruce Van Vliet

BioMedical Sciences
B.Sc. Toronto, Ph.D. Saskatchewan

Professor of Cardiovascular/Renal Physiology

Division of BioMedical Sciences,
Faculty of Medicine,
Memorial University of Newfoundland
Room: 4350, HSC

t: 709-864-4929
f: 709-864-6007

Dr. Van Vliet is interested in cardiovascular control mechanisms and, in particular, the regulation of blood pressure. His areas of investigation have included comparative physiology of the cardiovascular and respiratory systems, baroreceptors and baroreflexes, blood pressure variability, obesity, and autonomic mechanisms.

Dr. Van Vliet's current interests include:
Dr. Van Vliet's research has been supported by the Canadian Institutes of Health Research (CIHR), Memorial University of Newfoundland (MUN), and the Province of Newfoundland and Labrador.

Dr. Van Vliet is a member of M.U.N.’s Cardiovascular-Renal Research Group and Graduate Program.

People associated with the Van Vliet laboratory

Selected Publications: 

Van Vliet BN, Campbell NR; Canadian Hypertension Education Program. Efforts to reduce sodium intake in Canada: why, what, and when? Can J Cardiol. 2011 Jul-Aug;27(4):437-45.

McLoone V, Ringwood J, Van Vliet B. A 5-component mathematical model for salt-induced hypertension in Dahl-S and Dahl-R rats. Comput Methods Programs Biomed. 2011 Feb;101:220-9.

Mangourova V, Ringwood J, Van Vliet B. Graphical simulation environments for modelling and simulation of integrative physiology. Comput Methods Programs Biomed. Computer Methods and Programs in Biomedicine 2011 June; 102: 295-304

Montani JP, Van Vliet BN. Understanding the contribution of Guyton's large circulatory model to long-term control of arterial pressure. Exp Physiol. 2009 Apr;94(4):382-8 (Link to Pubmed)

McCormick D, Budgett DM, Lim MK, Van Vliet B, Nielsen PF, Hu AP, Malpas SC. Frequency response of implantable blood pressure telemetry systems. Clin Exp Pharmacol Physiol. 2010 Aug;37(8):862-9. (Link to Pubmed).
Vukolic A, Antic V, Van Vliet BN, Yang Z, Albrecht U, Montani JP. Role of mutation of the circadian clock gene Per2 in cardiovascular circadian rhythms. Am J Physiol Regul Integr Comp Physiol. 2010 Mar;298(3):R627-34. (Link to Pubmed).
McCloone VI, Ringwood JV, Van Vliet BN. A multi-component model of the dynamics of salt-induced hypertension in Dahl-S rats. BMC Physiol. 2009 Oct 29;9(1):20. [Epub ahead of print]

Van Vliet BN, Montani J-P. The Time Course of Salt-Induced Hypertension and Why it Matters. Int J Obesity. 2008; 32:S35-S47
(Link to PubMed).

Van Vliet BN, Guild S-J, Barrett C, McBryde F, Malpas S. Long-term recording of renal sympathetic nerve activity in conscious rats by telemetry. Experimental Biology 2008. FASEB J: 22:738.10 (Link to PubMed).

Van Vliet BN, Chafe LL. Effect of maternal eNOS genotype on blood pressure and activity in mice. Hypertension. 2007; Mar;49(3):556-62 (Link to PubMed).

Montani JP and VanVliet BN. Integrative Renal Regulation of Sodium Excretion. In: Sodium in Health and Disease. Michel Burnier (Ed). CRC Press, 2007.

Van Vliet BN, Chafe LL, Halfyard S, Leonard AM. Distinct rapid and slow phases of salt-induced hypertension in Dahl salt-sensitive rats. J Hypertension 24:1599-1606, 2006 (
Link to PubMed).

Leonard AM, Chafe LL, Montani J-P, Van Vliet BN. Increased salt-sensitivity in eNOS knockout mice. Am J Hypertens. 2006 Dec;19(12):1264-9 (
Link to PubMed).

Van Vliet BN, Chafe LL, Leonard AM, Joshi A, Montani J-P. Phenotying mouse blood pressure by telemetry. Clin Exp Pharm Physiol 2006; 33: 1007 - 1015 (
Link to PubMed).

Van Vliet BN and Montani JP. Circulation and Fluid Volume Control. In: Integrative Physiology. Humana Press, 2005.

Van Vliet BN, LL Chafe, J-P Montani. Characteristics of 24 h telemetered blood pressure in eNOS knockout and C57Bl/6J control mice. J Physiol (London) 549.1: 313 – 325, 2003 (
Link to PubMed).

Van Vliet B.N, Kiener-Belforti F, Montani J-P. Baroreflex stabilization of the double (pressure-rate) product at 0.05 Hz in conscious rabbits. Am J Physiol Regulatory Integrative and Comparative Physiology 282: R1746 - 1753, 2002 (
Link to PubMed).

Van Vliet BN, Chafe LL, Antic V, Schnyder-Candrian S, Montani J-P. Direct and indirect methods used to study arterial blood pressure. J Pharm Toxicol Methods 44: 361 - 373, 2000 (
Link to PubMed).

Van Vliet, B.N., L.L. Chafe, and J.P. Montani. Contribution of baroreceptors and chemoreceptors to ventricular hypertrophy produced by sino-aortic denervation in rats. J Physiol (London) 516: 885 - 895, 1999 (
Link to PubMed).

Van Vliet, B.N. and J.P. Montani. Baroreflex stabilization of the double product. Am J Physiol: Am J Physiol 277: H1679 - H1689, 1999 (
Link to PubMed).

Van Vliet, B.N., and N.H. West. Phylogenetic trends in the baroreceptor control of arterial blood pressure. Physiol Zool 67: 1284 - 1304, 1994.
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